Repeated Implantation Failure (RIF)

Repeated implantation failure is a case when a woman has been implanted with a good quality embryo at least three times, or has had a total of 10 or more embryos have been transplanted through several embryo transplants without resulting pregnancy.

Congenital uterine anomalies, uterine submucous myomas, uterine polyps, and endometrial adhesions can account for 25% to 50% of repeated implantation failures.

Hydrosalpinx results from an accumulation of secretions when the fallopian tube is occluded at its distal end (obstruction of the ampullary segment) or both ends and may cause infertility by blocking pathway of the embryo.

It is known that some antibodies related to the anti-phospholipid antibody syndrome may interfere with pregnancy.

If the quality of the oocyte or sperm is low, or if the chromosomes of the parents are abnormal, the embryo might not be suitable for implantation.

Other immunological factors may contribute to the cause.

Our hospital is able to identify these causes by parental chromosomal testing, vaginal ultrasound, fallopian tube examination, endoscopy, blood tests for thrombotic tendencies, and blood tests.

Smoking, weight management, and lifestyle changes such as alcohol abstinence can increase the rate of implantation.

A uterine cervix can be diagnosed to identify a uterine anomaly that can cause repeated implantation failure, and it can help the pregnancy rate by stimulating the endometrium.

You can increase the pregnancy rate by using test-tube conception and other assisted reproductive technology. Transplantation by selecting a normal embryo through a pre-implantation genetic test also helps to increase the pregnancy rate.

Repeated implantation failures can be caused by a variety of causes, and accurate diagnosis and treatment are essential. It is critical that you consult with a doctor who has sufficient experience to determine the direction of your future care.